University of Toronto
25 Harbord St., Toronto, ON M5S 3G5
- Pharmacogenetic approaches to studying the molecular basis of drug response variability
- Using computational tools to investigate GPCR-G protein selectivity by modelling interactions among GPCRs and G proteins
- H.B.Sc. (2018-Present) — University of Toronto Pharmacology and Toxicology, Computer Science
- University of Toronto Undergraduate Research Fund (2020)
- University of Toronto Admission Scholarship (2018)
- Advanced Placement Scholar with Honours (2018)
- Grade 12 Scholarship Cup (top 5 in the graduating class) (2018)
Oral and Poster Presentations
- Jing L., Chen S.K., Chang B.S.W. 2021. A Single-cell Approach to Addressing the Variable Drug Response Problem. Undergraduate Research Talks. University of Toronto Department of Cell and Systems Biology. (Oral presentation)
- Chen S.K., Jing L., Chang B.S.W. 2021. Deep mutational scanning of visual proteins in two dimensions. Vision Sciences 63rd Annual Research Day. University Health Network & University of Toronto Department of Vision Science, Virtual Conference. (Pre-recorded video presentation)
- Chen S.K., Jing L., Chang B.S.W. 2021. Investigating the molecular evolution of transmembrane proteins using high-throughput genetic approaches. International T3 Molecular Evolution Symposium (Tel Aviv, Toronto, Temple), Virtual Conference (Oral Presentation)
Project in Pharmacology (PCL472) – University of Toronto, Department of Pharmacology and Toxicology (2021-Present)
Research Opportunity Program (ROP299Y) – University of Toronto, Department of Cell & Systems Biology (2019-2020)
- As a continuation of my 2019 summer research internship, I worked on using a combination of microscopy, in vivo protein-protein interaction assays, and biochemical assays to provide evidence for the novel signaling mechanism in yeast.
- Helped to develop a deep scanning mutagenesis approach to study GPCRs using engineered yeast strains.
Summer Research Internship – University of Toronto, Department of Cell & Systems Biology (2019)
- Helped engineer a signal transduction system that couples human G protein-coupled receptors (GPCRs) to the yeast mating pathway with the goal of conducting high-throughput screens of GPCR mutants.
- Trained to use SciNet, Niagara, and Mist supercomputing clusters – SciNet Team (2021)
- Trained on Nikon imaging systems at University of Toronto Cell & Systems Biology – Plotnikov Lab (2019)
- Trained in microscopy image analysis (ImageJ (FIJI) microscopy analysis software) – Plotnikov Lab (2019)
- Trained in flow cytometry (MACSQuant VYB machine & FlowJo software) at University of Toronto Cell & Systems Biology – Chang Lab (2019)