- Whales Evolved Swiftly to Become Deep Divers July 7, 2022
- This Fish Has Adapted to Canada’s Deepest Coldest Lakes. UTSC Researchers are Unravelling it’s Genetics to Find Out How. July 7, 2022
- Convergent patterns of evolution of mitochondrial oxidative phosphorylation (OXPHOS) genes in electric fishes January 16, 2020
- Screening of Chemical Libraries Using a Yeast Model of Retinal Disease October 7, 2019
- Evolutionary signatures of photoreceptor transmutation in geckos reveal potential adaptation and convergence with snakes October 7, 2019
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Whales Evolved Swiftly to Become Deep Divers
Awesome news article from the CSB department at UofT highlighting a recent PNAS paper from the Chang lab, featuring the work of former PhD student Sarah Dungan! Many cetacean species can dive to extraordinary depths on a single breath, but … Continue reading
This Fish Has Adapted to Canada’s Deepest Coldest Lakes. UTSC Researchers are Unravelling it’s Genetics to Find Out How.
Great article from UTSC covering the incredible work Alex Van Nynatten, a postdoc in the Lovejoy lab, has been doing with the Deepwater Sculpin in collaboration with the Chang lab! This fish is quite impressive as they are known to … Continue reading
Convergent patterns of evolution of mitochondrial oxidative phosphorylation (OXPHOS) genes in electric fishes
The ability to generate and detect electric fields is vital for the survival of several groups of fishes. Authors Ahmed A. Elbassiouny, Nathan R. Lovejoy and Belinda S.W. Chang speculated that electric fish may be able to meet the high … Continue reading
Screening of Chemical Libraries Using a Yeast Model of Retinal Disease
Pathogenic mutations cause rhodopsin to misfold and disrupt its function. In this study, a yeast-based assay was used to screen for compounds that have the potential to rescue the function of mutant rhodopsin. It was confirmed that 9-cis retinal could … Continue reading
Evolutionary signatures of photoreceptor transmutation in geckos reveal potential adaptation and convergence with snakes
A recent study by Ryan K. Schott, Nihar Bhattacharyya, and Belinda S.W. Chang analysed the patterns of evolution in the gecko phototransduction gene and compared them to those of other reptiles. Parallel shifts in selective constraint on phototransduction genes were … Continue reading
To see or not to see: molecular evolution of the rhodopsin visual pigment in neotropical electric fishes
What do visual disease in humans and dim-light adaptation in fishes have in common? Read our publication on Proceedings of the Royal Society B, and find out more!
Coupling of human rhodopsin to a yeast signaling pathway
In this new assay, light dependent activation of the human rhodopsin protein initiates the yeast mating pathway and results in the signaling of a fluorescent reporter. This innovative technique allowed the authors to characterize a panel of known rhodopsin mutations … Continue reading
Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision
How did epistasis affect the evolution of tetrapod dim-light vision? How does this compare with fishes? Find out more by reading our lab’s recent paper published in eLIFE.
Bat cone opsin evolution
How is bat color vision shaped by ecological factors? Check out our new paper in Proc B!
Convergence in the visual system at high altitudes
Can convergence in evolutionary rates predict convergence in protein function? Check out our new paper in Evolution!